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Q.1) What does Osteoporosis mean?

Ans :  Osteoporosis means a decrease in the absolute amount of bone, resulting in brittleness of bones leading to fractures following minimal trauma.
  

Q.2) Whom does it affect the most?

Ans: It usually affects after 40 years of age, especially females at or after menopause.

   

Q.3) How does Osteoporosis progress?
Ans: It progresses due to an imbalance between the natural breakdown and replacement of bone tissue leading to a gradual decrease in the density and strength of the bone.
  
Q.4) What are the causes of Osteoporosis?
Ans: The causes are
  • Decline in sex hormone production with age.
  • Menopause.
  • Long-term treatment with oral Corticosteroids.
  • Rheumatoid arthritis.
  • Hyperthyroidism.
  • Chronic kidney failure.
  • Cushing's syndrome.
  • Anticonvulsant drug therapy.
  • Prolonged immobilization.
   
Q.5)What are the symptoms of Osteoporosis?
Ans: The symptoms are
  • Gradual loss of height.
  • Chronic backache.
  • Rounding of the back. [Thoracic kyphosis].
  • Fracture after a minor injury.
  
Q.6)what are the related signs?
Ans: The related signs are
  • Stress fractures.
  • Crush vertebral fractures.
    
Q.7)What investigations are done?
Ans: The tests conducted are
Blood tests
  • Serum alkaline phosphates.
  • Calcium and hydroxyproline ratio.
X-rays : especially of the limbs.
  
Q.8) What are the treatment measures?
Ans: Drugs generally used are
  • Conjugated estrogens.
  • Calcium and vitamin D
  • Proper management of fractures, if present
 
Q.9) What is the prognosis?
Ans: The prognosis is good with follow-up of proper medical treatment.
 
Q.10) How can Osteoporosis be prevented?
Ans: It can be prevented by
  • Eating a balanced diet rich in calcium and vitamin D throughout one's life.
  • Calcium supplementation during pregnancy, breast-feeding and after menopause.
  • Regular exposure to moderate amounts of sunlight. People exposed to little sunlight may need to take vitamin D supplements.
  • Walking and other forms of regular, moderate, weight-bearing exercise.
  • No smoking.
  • Limiting alcohol consumption.
  • Regular bone density measurement: especially in presence of risk factors.
  
Q.11) What are the Associated factors / risk factors?
Ans:  Risk factors for Osteoporosis
Endogenous
  • Thin physique.
  • Family history.
  • Early menopause.
  • Advanced age.
Exogenous
  • Low calcium intake.
  • Reduced physical activity.
  • Cigarette smoking.
  • Alcohol abuse.
  • Surgical menopause.
 
 

 

 

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