| Ans :  Osteoporosis means a decrease in the absolute amount of bone, resulting in brittleness of bones leading to fractures following minimal trauma. | 
                  
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                    | Q.2) Whom does it affect the most? | 
                  
                    | Ans: It usually affects
                     after 40 years of age, especially females at or after menopause. | 
                  
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                    | Q.3) How does Osteoporosis progress? | 
                  
                    | Ans: It progresses due to
                     an imbalance between the natural breakdown and replacement of bone tissue leading to a gradual decrease in the density and strength of the bone. | 
                  
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                    | Q.4) What are the causes of Osteoporosis? | 
                  
                    | Ans: The causes are 
                      Decline in sex hormone production with age.Menopause.Long-term treatment with oral Corticosteroids.Rheumatoid arthritis.Hyperthyroidism.Chronic kidney failure.Cushing's syndrome.Anticonvulsant drug therapy.Prolonged immobilization. | 
                  
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                    | Q.5)What are the symptoms of Osteoporosis? | 
                  
                    | Ans: The
                      symptoms are Gradual loss of height.
Chronic backache.
Rounding of the back. [Thoracic kyphosis].
Fracture after a minor injury.
 | 
                  
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                    | Q.6)what are the related signs? | 
                  
                    | Ans:
                      The related signs are Stress fractures.
Crush vertebral fractures.
 | 
                  
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                    | Q.7)What investigations are done? | 
                  
 | Ans: The tests
  conducted are | 
                  
 | Blood tests | 
                  
                    |  | 
                  
                    | Serum alkaline phosphates.
Calcium and hydroxyproline ratio.
 | 
                  
 | X-rays : especially of
  the limbs. | 
                  
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                    | Q.8) What are the treatment measures? | 
                  
                    | Ans: Drugs generally used are 
                      Conjugated estrogens.Calcium and vitamin DProper management of fractures, if present | 
                  
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                    | Q.9) What is the prognosis? | 
                  
                    | Ans: The prognosis is
                     good with follow-up of proper medical treatment. | 
                  
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                    | Q.10) How can Osteoporosis be prevented? | 
                  
                    | Ans: It can be prevented by 
                      Eating a balanced diet rich in calcium and vitamin D throughout
                        one's life.Calcium supplementation during pregnancy, breast-feeding and after menopause.Regular exposure to moderate amounts of sunlight. People exposed to little sunlight may need to take vitamin D supplements.Walking and other forms of regular, moderate, weight-bearing exercise.No smoking.Limiting alcohol consumption.Regular bone density measurement: especially in presence of risk factors. | 
                  
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                    | Q.11) What are the Associated factors / risk factors? | 
                  
 | Ans:  Risk factors for
  Osteoporosis | 
                  
 | Endogenous | 
                  
                    |  | 
                  
        | Thin physique.
Family history.
Early menopause.
Advanced age.
 | 
                  
 | Exogenous | 
                  
                    |  | 
                  
                    | Low calcium intake.
Reduced physical activity.
Cigarette smoking.
Alcohol abuse.
Surgical menopause.
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