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Ans : Aplastic anemia means a type of anemia caused by the failure of the bone marrow to produce new blood cells.
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Q.2) Whom does it affect the most?
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Ans: Age and gender is
not a significant factor in this disease.
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Q.3) What are the causes of Aplastic anemia? |
Ans: The causes are
- Abnormal genes
- Severe viral infection e.g.. Hepatitis
- Following Chemotherapy: Cytotoxic drugs
- Following Radiation
- Chemical exposure e.g.
- Benzene
- Toluene
- Chlorinated hydrocarbons
- Antibiotics e.g.
- Sulphonamides.
- Chloramphenicol.
- Anti-thyroid drugs
- Anti-rheumatic drugs.
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Q.4)What are the symptoms of Aplastic anemia? |
Ans: The symptoms are
- Fatigue
- Pale skin
- Breathlessness on mild exertion.
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Q.5)What investigations are done? |
Ans: The tests conducted are
- Complete blood count
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Haemoglobin
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Bone marrow aspiration
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Bone marrow biopsy
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Q.6) What are the related signs? |
Ans: The related signs are-
Peak incidence around 30 years.
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Insidious, onset
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Infections
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Haemorrhage: Haematuria and epistaxis.
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Intracranial bleeding.
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Necrotic mouth and throat ulcers.
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Q.7) What are the treatment measures? |
Ans: The treatment measures are
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Blood product support and aggressive management of infection.
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Bone marrow transplantation from a compatible donor.
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Q.8) What is the prognosis? |
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Ans:
The prognosis of severe aplastic anemia managed with supportive therapy only, is poor.
Prognosis is better after bone marrow transplantation,
especially in young patients.
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